Newly developed toothpaste reduces the risk of heart attack and stroke

Newly developed toothpaste reduces the risk of heart attack and stroke

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Protection against inflammation through newly developed toothpaste

Inflammation in the body seems to be related to our oral health. Can a newly developed toothpaste, which can identify plaque, reduce our risk of strokes and heart attacks by brushing the teeth more specifically?

A recent joint study by the Florida Atlantic University College of Medicine, the Marshfield Clinic Research Institute, and the University of Wisconsin School of Medicine and Public Health found that special toothpaste could reduce the risk of heart attacks and strokes. The results of the study were published in the English-language journal "American Journal of Medicine".

Relationship Between Oral Health And Inflammation?

For decades there have been various statements about a connection between our oral health and inflammation in the body. This is especially true for heart attacks and strokes.

What is hs-CRP?

Inflammation is closely involved in the pathogenesis of atherosclerosis and is accurately measured by the highly sensitive C-reactive protein (hs-CRP), a sensitive marker for the future risk of heart attack and stroke.

New toothpaste reduced hs-CRP in the body

The current study examined whether plaque-identifying toothpaste can actually reduce hs-CRP. The results show that the newly developed toothpaste called Plaque HD® brought about a statistically significant reduction in hs-CRP in people who had elevated protein levels at the start of the study.

New toothpaste weakens the core of the structure of plaque

Plaque HD® is the first toothpaste that identifies plaque so that it can be removed by targeted brushing. In addition, the product's proprietary formulation contains unique combinations and concentrations of ingredients that weaken the core of the plaque structure to help make the plaque visible and remove it more effectively.

How did the investigation work?

In the study, all participants adhered to an identical toothbrush protocol. Then they received toothpaste for 30 days - either Plaque HD® or an identical, non-plaque-identifying toothpaste. To assess the hs-CRP, the values ​​were measured using a so-called enzyme-linked immunosorbent test.

More research is needed

“Whether this plaque-identifying toothpaste reduces heart attacks or strokes requires a large-scale, randomized study of sufficient size and duration. These results provide a stronger reason for carrying out such studies. If the results were positive, the results of these studies would have significant potential effects on clinical and public health, ”says study author Professor Dr. Charles H. Hennekens of the College of Medicine at Florida Atlantic University in a press release.

Does toothpaste reduce the progression of atherosclerosis?

Another randomized study that has already been proposed is to examine whether Plaque HD® reduces the progression of atherosclerosis in the arteries, for which systemic inflammation is an important preliminary stage.

The risk increases especially in old age

Periodontal diseases increase with age, with more than 70 percent of adults aged 65 and older affected. Previous research has shown that periodontal disease can be linked to a variety of other diseases, including heart disease, stroke, and other inflammatory diseases such as rheumatoid arthritis.

Values ​​of hs-CRP could predict future heart attacks and strokes

Inflammation throughout the body can be a critical link between periodontitis and other systemic diseases. Another study on aspirin, inflammation, and cardiovascular disease has already suggested that the hs-CRP could predict future heart attacks and strokes. (as)

Author and source information

This text corresponds to the requirements of the medical literature, medical guidelines and current studies and has been checked by medical doctors.


  • Amit Acharya, BDS, MS, PhD, Ingrid Glurich, PhD, Scott Hetzel, MS, KyungMann Kim, PhD, Matthew C. Tattersall, DO, MS et al .: Correlation between Oral Health and Systemic Inflammation (COHESION): A Randomized Pilot Follow Up Trial of a Plaque Identifying Toothpaste, in American Journal of Medicine (Published 02/23/2020), American Journal of Medicine
  • Can a Toothpaste Save Your Life?, Florida Atlantic University (Published October 19, 2016), Florida Atlantic University

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